This Festschrift bears impressive testimony to the fascination which Icelandic and Norwegian sagas and Faroese ballads still exercise on researchers. Fifteen original papers examine central literary and historical aspects of Nordic sagas and ballads. The papers are published in German, English or Danish.

In the work of both Ludwik Fleck and Thomas Kuhn the scientific literature plays important roles for stability and change of scientific phenomenal worlds. In this article we shall introduce the analyses of scientific literature provided by Fleck and Kuhn, respectively. From this background we shall discuss the problem of how divergent thinking can emerge in a dogmatic atmosphere. We shall argue that in their accounts of the factors inducing changes of scientific phenomenal worlds Fleck and Kuhn offer substantially different (...) approaches, and we shall discuss in which respects their approaches may be compatible. (shrink)

BackgroundAntipsychotic-induced weight gain is a contributing factor in the reduced life expectancy reported amongst people with psychotic disorders. CYP2D6 is a liver enzyme involved in the metabolism of many commonly used antipsychotic medications. We investigated if CYP2D6 genetic variation influenced weight or BMI among people taking antipsychotic treatment.MethodsWe conducted a systematic review and a random effects meta-analysis of publications in Pubmed, Embase, PsychInfo, and CENTRAAL that had BMI and/or weight measurements of patients on long-term antipsychotics by their CYP2D6-defined metabolic groups.ResultsTwelve (...) studies were included in the systematic review. All cohort studies suggested that the presence of reduced-function or non-functional alleles for CYP2D6 was associated with greater antipsychotic-induced weight gain, whereas most cross-sectional studies did not find any significant associations. Seventeen studies were included in the meta-analysis with clinical data of 2,041 patients, including 93 poor metabolizers, 633 intermediate metabolizers, 1,272 normal metabolizers, and 30 UMs. Overall, we did not find associations in any of the comparisons made. The estimated pooled standardized differences for the following comparisons were PM versus NM; weight = –0.07, BMI = 0.40. IM versus NM; weight = 0.09 and BMI = 0.09. UM versus EM; weight = 0.01 and BMI = –0.08.ConclusionOur systematic review of cohort studies suggested that CYP2D6 poor metabolizers have higher BMI than normal metabolizers, but the data of cross-sectional studies and the meta-analysis did not show this association. Although our review and meta-analysis constitutes one of the largest studies with comprehensively genotyped samples, the literature is still limited by small numbers of participants with genetic variants resulting in poor or UMs status. We need further studies with larger numbers of extreme metabolizers to establish its clinical utility in antipsychotic treatment. CYP2D6 is a key gene for personalized prescribing in mental health. (shrink)

BackgroundDecision-making in out-of-hospital cardiac arrest should ideally include clinical and ethical factors. Little is known about the extent of ethical considerations and their influence on prehospital resuscitation. We aimed to determine the transparency in medical records regarding decision-making in prehospital resuscitation with a specific focus on ethically relevant information and consideration in resuscitation providers’ documentation.MethodsThis was a Danish nationwide retrospective observational study of out-of-hospital cardiac arrests from 2016 through 2018. After an initial screening using broadly defined inclusion criteria, two experienced (...) philosophers performed a qualitative content analysis of the included medical records according to a preliminary codebook. We identified ethically relevant content in free-text fields and categorised the information according to Beauchamp and Childress’ four basic bioethical principles: autonomy, non-maleficence, beneficence, and justice. ResultsOf 16,495 medical records, we identified 759 (4.6%) with potentially relevant information; 710 records (4.3%) contained ethically relevant information, whereas 49 did not. In general, the documentation was vague and unclear. We identified four kinds of ethically relevant information: patients’ wishes and perspectives on life; relatives’ wishes and perspectives on patients’ life; healthcare professionals’ opinions and perspectives on resuscitation; and do-not-resuscitate orders. We identified some “best practice” examples that included all perspectives of decision-making. ConclusionsThere is sparse and unclear evidence on ethically relevant information in the medical records documenting resuscitation after out-of-hospital cardiac arrests. However, the “best practice” examples show that providing sufficient documentation of decision-making is, in fact, feasible. To ensure transparency surrounding prehospital decisions in cardiac arrests, we believe that it is necessary to ensure more systematic documentation of decision-making in prehospital resuscitation. (shrink)

This collection of essays in honor of Prof. Stig Andur Pedersen's 60th Birthday spans over a broad scope of topics, ranging from mathematical modelling over realism in philosophy of science to an analysis of apology after medical mistakes. The unusually broad range is a fair but still inadequate reflection of the work of Stig Andur Pedersen, a philosopher and scientist whose range of interests, abilities and production is itself unusually broad.

One important problem concerning incommensurability is how to explain that two theories which are incommensurable and therefore mutually untranslatable and incomparable in a strictly logical, point-by-point way are still competing. The two standard approaches have been to argue either that the terms of incommensurable theories may share reference, or that incommensurable theories target roughly the same object domain as far as the world-in-itself is concerned. However, neither of these approaches to the problem pay due respect to the incommensurability thesis' insights. (...) In this paper I shall first show the inconsistency between the basic premises underlying Kuhn’s incommensurability thesis and the two standard responses to the thesis. I shall then argue that if one adopts Kuhn’s position, the response must build on a notion of overlap between phenomenal worlds. Finally, I shall argue that overlap between complex structures of features can provide the basis for such a notion, and that this makes it possible to explain how incommensurable theories may compete. (shrink)

The Golden Age of postwar capitalism has been eclipsed, and with it seemingly also the possibility of harmonizing equality and welfare with efficiency and jobs. Most analyses believe that the emerging postindustrial society is overdetermined by massive, convergent forces, such as tertiarization, new technologies, or globalization, all conspiring to make welfare states unsustainable in the future. Social Foundations of Postindustrial Economies takes a second, more sociological and more institutional, look at the driving forces of economic transformation. What, as a result, (...) stands out is postindustrial diversity, not convergence. Macroscopic, global trends are undoubtedly powerful, yet their influence is easily rivalled by domestic institutional traditions, by the kind of welfare regime that, some generations ago, was put in place. It is, however, especially the family economy that hold the key as to what kind of postindustrial model will emerge, and to how evolving tradeoffs will be managed. Twentieth-century economic analysis depended on a set of sociological assumptions that, now, are invalid. Hence, to better grasp what drives today's economy, we must begin with its social foundations. (shrink)

Name der Zeitschrift: Semiotica Jahrgang: 2018 Heft: 225 Seiten: 77-102.

Recently, several scholars have argued that scientists can accept scientific claims in a collective process, and that the capacity of scientific groups to form joint acceptances is linked to a functional division of labor between the group members. However, these accounts reveal little about how the cognitive content of the jointly accepted claim is formed, and how group members depend on each other in this process. In this paper, I shall therefore argue that we need to link analyses of joint (...) acceptance with analyses of distributed cognition. To sketch how this can be done, I shall present a detailed case study, and on the basis of the case, analyze the process through which a group of scientists jointly accept a new scientific claim and at a later stage jointly accept to revise previously accepted claims. I shall argue that joint acceptance in science can be established in situations where an overall conceptual structure is jointly accepted by a group of scientists while detailed parts of it are distributed among group members with different areas of expertise, a condition that I shall call a heterogeneous conceptual consensus. Finally, I shall show how a heterogeneous conceptual consensus can work as a constraint against scientific change and address the question how changes may nevertheless occur. (shrink)

`Proto-idea' was a central concept in the thinking of the Polish microbiologist and philosopher of science Ludwik Fleck (1896–1961). Based on studies of the origin of the modern concept of syphilis, Fleck claimed that many established scientific facts are best understood as interpretations of pre scientific, somewhat hazy `proto-ideas' in the framework of a certain `thought-style'. As an example,Fleck saw the modern knowledge of infection as an interpretation of the ancient proto-idea of diseases as caused by minute `animalcules'. However, the (...) epistemological aspects of the concept of proto-ideas have only been sparsely developed and discussed by Fleck and his critics. This paper attempts to bridge the gap. Firstly, I reconstruct the concept of proto-ideasin the context of Fleck's constructivist theory of knowledge. Secondly, I illustrate the relation between Fleck's concept of proto-ideas and his nominalist view on medical taxonomy. Finally, I discuss four philosophical problems implied by Fleck's concept of proto-ideas: (a) the problem of combining two conflicting perspectives on the history of science (b) the problem of accounting for the notion of` continuity' within a non realist theory of knowledge (c) the problem of ascribing no truth-content to proto-ideas, and (d) the problem concerning the non-neutrality of the analyst's viewpoint. (shrink)

Scientific Change How do scientific theories, concepts and methods change over time? Answers to this question have historical parts and philosophical parts. There can be descriptive accounts of the recorded differences over time of particular theories, concepts, and methods—what might be called the shape of scientific change. Many stories of scientific change attempt to give […].

The content of this book is essentially one argument. The aim of this book is to consider the breakdown of a certain world view during the twentieth century. This is mirrored in the treatment of both science and philosophy. As these form the foundation for the human position in the world, a major reorganization of the body of knowledge had to take place. Bohr and Wittgenstein have been chosen as the main actors to represent this revision. Each one had to (...) replace apparent order and certainty by an understanding based on limited concepts in constant flux. The conclusion is that the modern synthesis is far from satisfactory. By leaving the story unfinished in its present state, the book hopes to provoke a renewal of the discussion and the eventual emergence of a reformed clarity and understanding. Reality is to be left as it is, but the human mind is also to be left as it is. The problem is to find a way to effect a harmonious combination of these. (shrink)

It is a commonly raised argument against the family resemblance account of concepts that there is no limit to a concept's extension. An account of family resemblance which attempts to provide a solution to this problem by including both similarity among instances and dissimilarity to non-instances has been developed by the philosopher of science Thomas Kuhn. Similar solutions have been hinted at in the literature on family resemblance concepts, but the solution has never received a detailed investigation. I shall provide (...) a reconstruction of Kuhn's theory and argue that his solution necessitates a developmental perspective wchich builds on both the transmission of taxonomies between generations and a progressive development through history. (shrink)

We consider the concept of entanglement for pure cases of finite dimensional state spaces. The criterion of unentangled states is related to demanding rank one of an associated eigenvalue problem. In addition to the conventional procedure based on the Schmidt decomposition, we devise a method based on the spectral resolution of unsymmetric matrices. In particular, we consider the case when all eigenvalues are zero, and find that the method still works.

This paper discusses the Uniqueness Thesis, a core thesis in the epistemology of disagreement. After presenting uniqueness and clarifying relevant terms, a novel counterexample to the thesis will be introduced. This counterexample involves logical disagreement. Several objections to the counterexample are then considered, and it is argued that the best responses to the counterexample all undermine the initial motivation for uniqueness.

The article presents a particular case of undergraduate students working on subprojects within the framework of their supervisors' (the authors') research project during Autumn Semester 2012 and Spring Semester 2013. The article's purpose is to show that an institutionalized focus on students as "research learners" rather than merely curriculum learners proves productive for both research and teaching. We describe the specific university learning context and the particular organization of undergraduate students' supervision and assistantships. The case builds on and further enhances (...) a well-established and proven university model of participant-directed, problem-oriented project work. We explore students' and researchers' experiences of being part of the collaboration, focusing on learning potentials and dilemmas associated with the multiple roles of researcher and student that characterized this particular intertwined research and education arrangement. We show that the connection to the research project assisted students to orientate, learn, and contribute in relation to empirical and theoretical aspects of research and supported the development of broad perspectives and deep analysis. (shrink)

Ernst Jünger is known for his war writings, but is largely ignored by contemporary phenomenologists. In this essay, I explore his e Adventurous Heart which has recently been made available in English. is work consists of a set of fragments which, when related, disclose a coherent ow of philosophical thinking. Speci cally, I show that, beneath a highly poetic and obscure prose, Jünger posits how subjective experience and poetry allow individuals to realize truth. I relate parts of Jünger’s insights to (...) contributions by Husserl, Heidegger and Merleau-Ponty, arguing that Jünger o ers a unique and valuable contribution to the phenomenological discipline. (shrink)

This article studies the Islamic State's only remaining periodical, Al-Naba, identifying the most common tropes and patterns in the periodical's Sub-Saharan Africa coverage, and on Mozambique in particular. The Islamic State's increasingly important coverage of Africa focuses on terror attacks, military campaigns and on the fight against Christianity. However, it also employs more traditional anti-colonial arguments that have been used by other, more accepted, political actors during the struggle for decolonisation. Al-Naba also functions as a 'shamer' of non-African Muslims, to (...) get them to join jihad by pointing to the African successes of the organisation and set these successes up as examples to be followed. In this sense, the article illustrates how African jihadist branches can have global agency. (shrink)

Open peer commentary on the article “Lived Experience and Cognitive Science Reappraising Enactivism’s Jonasian Turn” by Mario Villalobos & Dave Ward. Upshot: We argue that Villalobos and Ward’s criticism misses two crucial aspects of Varelian enactivism. These are, first, that enactivism attempts to offer a rigorous scientific justification for its teleological claims, and second, that enactivism in fact pays too little attention to the nature of human phenomenology and intentionality, rather than anthropomorphically over-valuing it.

This paper extends Mori’s (IEEE Robot Autom Mag 19:98–100, 2012) uncanny valley-hypothesis to include technologies that fail its basic criterion that uncanniness arises when the subject experiences a discrepancy in a machine’s human likeness. In so doing, the paper considers Mori’s hypothesis about the uncanny valley as an instance of what Heidegger calls the ‘challenging revealing’ nature of modern technology. It introduces seeming autonomy and heteronomy as phenomenological categories that ground human being-in-the-world including our experience of things and people. It (...) is suggested that this categorical distinction is more foundational than Heidegger’s existential structures and phenomenological categories. Having introduced this novel phenomenological distinction, the paper considers the limits of Mori’s hypothesis by drawing on an example from science fiction that showcases that uncanniness need not only be caused by machines that resemble human beings. In so doing, it explores how the seeming autonomy-heteronomy distinction clarifies (at least some of) the uncanniness that can arise when humans encounter advanced technology which is irreducible to the anthropocentrism that shapes Mori’s original hypothesis. (shrink)

Technology is increasingly subject of attention from philosophers. Philosophical reflection on technology exhibits a wide and at times bewildering array of approaches and modes of thought. This volume brings to light the development of three schools in the philosophy of technology. Based on thorough introductions to Karl Marx', Martin Heidegger's and John Dewey's thought about technology, the volume offers an in-depth account of the way thinkers in the critical, the phenomenological and the pragmatic schools have respond to issues and challenges (...) raised by the works of the founders of these schools. Technologies in almost any aspect of human life is potentially subject of philosophical treatment. To offer a focused demonstration of key arguments and insights, the presentation of each school is concluded with a contribution to discussions of educational technologies. In addition to philosophers seeking a valuable and clear structuring of a still burgeoning field, the volume is of interest to those working with educational philosophy and value sensitive design. „Stig Børsen Hansen’s book is a must for all interested in understanding the development of the philosophy of technology and the relation of thoughts of thinkers that have shaped the area. The author presents a new and refreshing take on the ideas from Marx to Marcuse, from Dewey to Latour, and Heidegger to Borgmann. It will engage and hopefully provoke." Dr. Jan Kyrre Berg Friis, University of Copenhagen. (shrink)

Many degree programs in science and engineering aim at enabling their students to perform interdisciplinary problem solving. In this paper we present three types of expertise that are involved in different ways in interdisciplinary problem solving. In doing so we shall first characterise two important epistemological challenges commonly faced in interdisciplinary problem solving, namely the communication challenge that arises from the use of different concepts within different scientific domains, and the integration challenge that arises from the differences between domain-specific epistemological (...) standards. Next, drawing on recent work on expertise developed within science studies, we characterize the interactional expertise that is a precondition for scientists to communicate across scientific domains, and the integrational expertise that is a precondition for scientists to be able to integrate cognitive resources originating in different domains. Finally, we shall analyse how different types of interdisciplinary problem solving sets different requirements for interactional and integrational expertise and discuss the implications for science and engineering programs in higher education. (shrink)